The use of plutonium (Pu(IV) for military and civil applications can lead to internal contamination. There are several possible routes of contamination: ingestion, inhalation or injury. In case of plutonium inhalation, the plutonium forms oxide particles that reach the pulmonary alveoli. Through a phagocytosis mechanism, the particles are...
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November 22, 2018 (v1)PublicationUploaded on: December 4, 2022
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January 11, 2018 (v1)Conference paper
Actinides elements (that are all radioactive) are the subject of special attention considering the important amount that has been produced for military and civil applications. They often present a dual toxicity: chemical and radiotoxicological from α and β decay. In case of dissemination during an accidental nuclear event, the consequences of...
Uploaded on: December 4, 2022 -
2020 (v1)Journal article
Plutonium (Pu) is an anthropogenic element involved in the nuclear industry cycle. Located at the bottom of the periodic table within the actinide family, it is a chemical toxic but also a radiological toxic, regardless of isotopy. After nearly 80 years of Pu industrialization, it has become clear that inhalation and wounds represent the two...
Uploaded on: December 4, 2022 -
2018 (v1)Journal article
Since the 1940s, great amounts of Plutonium (Pu) have been produced for both military and civil purposes. Until now, the standard therapy for decorporation following inhalation has been the intravenous injection of diethylenetriaminepentaacetic acid ligand (Ca-DTPA form). This method offers a strong complexing constant for Pu(IV) but has poor...
Uploaded on: December 4, 2022