LÓPEZ ENRÍQUEZ , Soledad

High-density lipoproteins (HDLs) are heterogeneous lipoproteins that modify their composition and functionality depending on physiological or pathological conditions. The main roles of HDL are cholesterol efflux, and anti-inflammatory and antioxidant functions. These functions can be compromised under pathological conditions. HDLs play a role...

La presente invención está dirigida al uso de los gens/es MyD88y/o TL3 para el diagnóstico, pronóstico y/o seguimiento de la esclerosis lateral amiotrófica (ELA), a un método de obtención de datos útiles para el diagnóstico, pronóstico y/o seguimiento de la ELA, kit o dispositivo y usos.

Dendritic cells (DCs) serve as professional antigen-presenting cells (APC) bridging innate and adaptive immunity, playing an essential role in triggering specific cellular and humoral responses against tumor and infectious antigens. Consequently, various DC-based antitumor therapeutic strategies have been developed, particularly vaccines, and...

Pluripotent stem cells maintain the property of self-renewal and differentiate into all cell types under clear environments. Though the gene regulatory mechanism for pluripotency has been investigated in recent years, it is still not completely understood. Here, we show several signaling pathways involved in the maintenance of pluripotency. To...