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LÜCKERATH , Katharina

Last name: LÜCKERATH

First name: Katharina

January 13, 2011 (v1)

Journal article

Metadata-only

Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain.

Lückerath, Katharina Kirkin, Vladimir Melzer, Inga Maria

Fas Ligand (FasL) not only induces apoptosis in Fas receptor-bearing target cells, it is also able to transmit signals into the FasL-expressing cell via its intracellular domain (ICD). Recently, we described a Notch-like proteolytic processing of FasL that leads to the release of the FasL intracellular domain (ICD) into the cytoplasm and...

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