LOI , Giulia

Heme oxygenase 1 (HO-1) is widely recognized as a protective enzyme that counteracts cell damage through the antioxidant, antiapoptotic and anti-inflammatory activity of its metabolic products. By increasing cell resistance to stressors, HO-1 induction has been related with the gain of resistance and progression of different types of cancers...

Heme oxygenase 1 (HO-1) plays a pivotal role in preventing cell damage. Indeed, through the antioxidant, antiapoptotic and anti-inflammatory properties of its metabolic products, it favors cell adaptation against different stressors. However, HO-1 induction has also been related to the gain of resistance to therapy in different types of cancers...