LABARTHE , Simon

The gut microbiota, mainly located in the colon, is engaged in a complex dialogue with the large intestinal epithelium through which important regulatory processes for the health and well-being of the host take place. Imbalances of the microbial populations, called dysbiosis, are related to several pathological status, emphasizing the...

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We introduce a mixture model intended to describe the dynamics of the mucus layer that wraps the gut mucosa. This model takes into account the fluid mechanics of the gut content, the inhomogeneous rheology that depends on the fluid composition, and the main physiological mechanisms that ensure the homoeostasis of the mucus layer. Numerical...