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LACAGNE , Iliona

Last name: LACAGNE

First name: Iliona

September 27, 2022 (v1)

Journal article

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Combining affinity purification and mass spectrometry to define the network of the nuclear proteins interacting with the N-terminal region of FMRP

Kieffer, Félicie Hilal, Fahd Gay, Anne-Sophie

Fragile X-Syndrome (FXS) represents the most common inherited form of intellectual disability and the leading monogenic cause of Autism Spectrum Disorders. In most cases, this disease results from the absence of expression of the protein FMRP encoded by the FMR1 gene (Fragile X messenger ribonucleoprotein 1). FMRP is mainly defined as a...

Uploaded on: December 4, 2022
July 2022 (v1)

Journal article

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Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors

Pronot, Marie Poupon, Gwénola Pizzamiglio, Lara

SUMOylation is a post-translational modification essential to cell homeostasis. A tightly controlled equilibrium between SUMOylation and deSUMOylation processes is also critical to the neuronal function including neurotransmitter release and synaptic transmission and plasticity. Disruption of the SUMOylation homeostasis in neurons is associated...

Uploaded on: December 3, 2022