LACHAUD , Christian

Les écrans cathodiques, dont l'usage s'est généralisé à la grande majorité de la population occidentale, sont responsables de troubles variés (maux de tête, fatigue visuelle, chute des performances cognitives, etc.), dont la gravité peut aller jusqu'au syndrome neurologique chez les sujets prédisposés (déclenchement de crises d'épilepsie). Si...

Certains enseignements spirituels de l'Inde (Soufisme, Raja Yoga) se fondent sur l'utilisation de transmission de Prana, ou énergie spirituelle, appelée ici « transmission ». Le Yoga se présente comme une technique pratique, à la fois rationnelle et irrationnelle. Rationnelle par sa logique et sa méthode, entièrement fondées du point de vue...

Recent studies suggested that the post-natal mesothelium retain differentiative potential of the embryonic mesothelium, which generates fibroblasts and vascular smooth muscle cells (VSMCs), in developing coelomic organs via epithelial-to-mesenchymal transition (EMT). Whether adult mesothelial cells (MCs) are able to give rise to functional...

Human embryonic stem cells (hESCs) retain the extraordinary capacity to differentiate into different cell types of an adult organism, including pancreatic β-cells. For this particular lineage, although a lot of effort has been made in the last ten years to achieve an efficient and reproducible differentiation protocol, it was not until recently...

Human pluripotent stem cells retain the extraordinary capacity to differentiate into pancreatic beta cells. For this particular lineage, more effort is still required to stress the importance of developing an efficient, reproducible, easy, and cost-effective differentiation protocol to obtain more mature, homogeneous, and functional...

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In recent years, it has become accepted that α-synuclein (αSyn) has a key role in the microglia-mediated neuroinflammation, which accompanies the development of Parkinson's disease and other related disorders, such as Dementia with Lewy Bodies and Alzheimer's disease. Nevertheless, the cellular and molecular mechanisms underlying its...

Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies focused on repressing the immune attack or stimulating beta cell regeneration still have limited clinical efficacy. Therefore, it is timely to identify innovative targets to dampen the immune process, while promoting...