2002 (v1)
Journal article
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2002 (v1)Journal article
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July 2, 1999 (v1)Journal article
Secreted phospholipases A2 (sPLA2s) form a class of structurally related enzymes that are involved in a variety of physiological and pathological effects including inflammation and associated diseases, cell proliferation, cell adhesion, and cancer, and are now known to bind to specific membrane receptors. Here, we report the cloning and...
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2003 (v1)Journal article
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2003 (v1)Journal article
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2003 (v1)Journal article
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2003 (v1)Journal article
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2005 (v1)Journal article
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January 2007 (v1)Journal article
We investigated the hydrolysis of the minor glycerophospholipids of human HDL(3), total HDL and LDL using human group IIA, V and X secretory phospholipases A(2) (sPLA(2)s). For this purpose we employed the enzyme and substrate concentrations and incubation times optimized for hydrolysis of phosphatidylcholine (PtdCho), the major...
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2006 (v1)Journal article
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2006 (v1)Journal article
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2005 (v1)Journal article
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2003 (v1)Journal article
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2003 (v1)Journal article
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2002 (v1)Journal article
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2002 (v1)Journal article
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2006 (v1)Journal article
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2005 (v1)Journal article
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February 12, 2008 (v1)Journal article
Recent studies suggest that secreted phospholipases A2 (sPLA2s) represent attractive potential tumour biomarkers and therapeutic targets for various cancers. As a first step to address this issue in human colorectal cancer, we examined the expression of the full set of sPLA2s in sporadic adenocarcinomas and normal matched mucosa from 21...
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2005 (v1)Journal article
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2006 (v1)Journal article
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