LAMY , Brigitte

Aeromonas is at the interface of all the One Health components and represents an amazingly sound test case in the One Health approach, from economic loss in aquaculture tochallenges related to antibiotic-resistant bacteria selected from the environment. In human health, infections following leech therapy is an outstanding example of such One...

Background: Bloodstream infection (BSI) is a major public health burden worldwide, with high mortality. Patient outcome is critically influenced by delayed therapy, and fast and accurate pathogen diagnostics decisively improves the care of patients. During the past two decades major improvements have been made in the diagnostic performance of...

Background: Leech therapy in plastic/reconstructive microsurgery significantly improves a successful outcome of flap salvage but the drawback is a risk of severe infection that results in a drop of the salvage rates from 70-80% to below 30%. We report the results of a national survey conducted in all the French university hospitals to assess...

International audience

Background: Staphylococcus saccharolyticus is a rarely encountered coagulase-negative, which grows slowly and its strictly anaerobic staphylococcus from the skin. It is usually considered a contaminant, but some rare reports have described deep-seated infections. Virulence factors remain poorly known, although, genomic analysis highlights...

International audience

Fluoroquinolones (FQs) and ciprofloxacin (Cp) are important antimicrobials that pollute the environment in trace amounts. Although Cp has been recommended as prophylaxis for patients undergoing leech therapy to prevent infections by the leech gut symbiont Aeromonas, a puzzling rise in Cp-resistant (Cp r) Aeromonas infections has been reported....

Antimicrobial resistance (AMR) is now considered to be a major public health issue. AMR needs to be tackled following a One Health approach. With regard to antibiotic use and anthropic activity, fish farming is an appealing model to study the effects of antibiotic exposure on the rise of AMR. Aeromonas is at the interface of all the One Health...

The identification of Aeromonas isolates to species level remains a challenge. Sequencing of housekeeping genes (gyrB, rpoB...) is considered the gold standard. However, these methods are costly and time-consuming. Pérez-Sancho et al. (2018) demonstrated the utility of MALDI-TOF MS (MT) for the identification of Aeromonas at the genus level,...