LANDI G.

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Trypanosoma and Leishmania parasites are the etiological agents of various threatening neglected tropical diseases (NTDs), including human African trypanosomiasis (HAT), Chagas disease, and various types of leishmaniasis. Recently, meaningful progresses in the treatment of HAT, due to Trypanosoma brucei (Tb), have been achieved by the...

Satellite communications (SatCom) have a role of advanced service enablers in the new virtual networks, following 3GPP specifications. Specifically, the satellite peculiar characteristics are of paramount importance to dynamically activate capabilities, such as multicast and broadcast channels, sudden traffic offloading, capacity bonding, and...

Background. On 22 December 2017, Law No. 219 was approved in Italy entitled "Provisions on informed consent and advance treatment directives". This article reports the results from a survey of the knowledge of medico-legal experts in Italy on these provisions, in addition to the ability of university health-care facilities in Italy to implement...

Folate enzymes, namely, dihydrofolate reductase (DHFR) and pteridine reductase (PTR1) are acknowledged targets for the development of antiparasitic agents against Trypanosomiasis and Leishmaniasis. Based on the amino dihydrotriazine motif of the drug Cycloguanil (Cyc), a known inhibitor of both folate enzymes, we have identified two novel...