International audience
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September 2021 (v1)Journal articleUploaded on: December 4, 2022
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September 2021 (v1)Journal article
International audience
Uploaded on: February 22, 2023 -
September 2021 (v1)Journal article
International audience
Uploaded on: February 22, 2023 -
September 2021 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
September 2021 (v1)Journal article
Activation and sensitization of trigeminal ganglia (TG) sensory neurons, leading to the release of pro-inflammatory peptides such as calcitonin gene-related peptide (CGRP), are likely a key component in migraine-related headache induction. Reducing TG neuron excitability represents therefore an attractive alternative strategy to relieve...
Uploaded on: December 3, 2022 -
September 2021 (v1)Journal article
Activation and sensitization of trigeminal ganglia (TG) sensory neurons, leading to the release of pro-inflammatory peptides such as calcitonin gene-related peptide (CGRP), are likely a key component in migraine-related headache induction. Reducing TG neuron excitability represents therefore an attractive alternative strategy to relieve...
Uploaded on: December 3, 2022 -
December 2023 (v1)Journal articleA photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals
Abstract By endowing light control of neuronal activity, optogenetics and photopharmacology are powerful methods notably used to probe the transmission of pain signals. However, costs, animal handling and ethical issues have reduced their dissemination and routine use. Here we report LAKI (Light Activated K + channel Inhibitor), a specific...
Uploaded on: March 25, 2023 -
December 2023 (v1)Journal articleA photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals
Abstract By endowing light control of neuronal activity, optogenetics and photopharmacology are powerful methods notably used to probe the transmission of pain signals. However, costs, animal handling and ethical issues have reduced their dissemination and routine use. Here we report LAKI (Light Activated K + channel Inhibitor), a specific...
Uploaded on: May 4, 2023