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LELIANOVA , Vera G

Last name: LELIANOVA

First name: Vera G

2022 (v1)

Publication

Metadata-only

ADGRL1 haploinsufficiency causes a variable spectrum of neurodevelopmental disorders in humans and alters synaptic activity and behavior in a mouse model

Vitobello, Antonio Mazel, Benoit Lelianova, Vera G

ADGRL1 (latrophilin 1), a well-characterized adhesion G protein-coupled receptor, has been implicated in synaptic development, maturation, and activity. However, the role of ADGRL1 in human disease has been elusive. Here, we describe ten individuals with variable neurodevelopmental features including developmental delay, intellectual...

Uploaded on: February 4, 2024