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LEONE , Biagio Eugenio

Last name: LEONE

First name: Biagio Eugenio

2023 (v1)

Publication

Metadata-only

Myelomonocytic cells in giant cell arteritis activate trained immunity programs sustaining inflammation and cytokine production

Cantoni, Eleonora Merelli, Ivan Stefanoni, Davide

Objective Trained immunity (TI) is a de facto memory program of innate immune cells, characterized by immunometabolic and epigenetic changes sustaining enhanced production of cytokines. TI evolved as a protective mechanism against infections; however, inappropriate activation can cause detrimental inflammation and might be implicated in the...

Uploaded on: February 23, 2024