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LESTRAT , C.

Last name: LESTRAT

First name: C.

September 16, 2010 (v1)

Journal article

Metadata-only

Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers.

Caron, C. Lestrat, C. Marsal, S.

Cancer cells frequently express genes normally active in male germ cells. ATAD2 is one of them encoding a conserved factor harbouring an AAA type ATPase domain and a bromodomain. We show here that ATAD2 is highly expressed in testis as well as in many cancers of different origins and that its high expression is a strong predictor of rapid...

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