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LETIZIA TARANTINI

Last name: LETIZIA TARANTINI

2023 (v1)

Publication

Metadata-only

Let-7a Downregulation Accompanied by KRAS Mutation Is Predictive of Lung Cancer Onset in Cigarette Smoke–Exposed Mice

Alessandra Pulliero Luca Mastracci Letizia Tarantini

Background: Let-7 is a tumor suppressor microRNA targeting the KRAS lung oncogene. Let-7a downregulation is reversible during the early stages of lung carcinogenesis but is irreversible in cancer cells. The aim of this study is to shed light on the relationship between oncogene (KRAS) mutation and let-7a downregulation in cigarette smoke...

Uploaded on: January 31, 2024