2013 (v1)
Journal article
International audience
Uploaded on: December 2, 2022
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2013 (v1)Journal article
International audience
Uploaded on: October 11, 2023 -
November 1, 2009 (v1)Journal article
The senile plaques found in the brains of patients with Alzheimer's disease are mainly due to the accumulation of amyloid beta-peptides (A beta) that are liberated by gamma-secretase, a high molecular weight complex including presenilins, PEN-2, APH-1 and nicastrin. The depletion of each of these proteins disrupts the complex assembly into a...
Uploaded on: December 4, 2022