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LISOWSKI , Vincent

Last name: LISOWSKI

First name: Vincent

October 19, 2005 (v1)

Journal article

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Design and characterization of a new cell-permanent inhibitor of the ß-secretase BACE1

Checler, Frédéric Hernandez, Jean-François Lefranc-Julien, Solveig

International audience

Uploaded on: February 28, 2023
November 20, 2007 (v1)

Conference paper

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Activités gamma-secrétase et présénilinase impliquées dans la maladie d'Alzheimer : mise au point de substrats fluorimétriques et d'inhibiteurs

Checlerc, Frédéric Sévalle, Jean Lisowski, Vincent

No description

Uploaded on: December 3, 2022
February 2013 (v1)

Journal article

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Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein

Peuchmaur, Marine Lacour, Marie-Agnès Sévalle, Jean

The 3-alkoxy-7-amino-4-chloro-isocoumarins JLK-6 and JLK-2 have been shown to markedly reduce the production of Amyloid β-peptide (Aβ) by Amyloid-β Precursor Protein (APP) expressing HEK293 cells by affecting the γ-secretase cleavage of APP, with no effect on the cleavage of the Notch receptor. This suggested that these compounds do not...

Uploaded on: December 3, 2022