Calcins are a group of scorpion toxin peptides specifically binding to ryanodine receptors (RyRs) with high affinity, and have the ability to activate and stabilize RyR in a long-lasting subconductance state. Five newly calcins synthesized compounds exhibit typical structural characteristics of a specific family through chemical synthesis and...
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2024 (v1)PublicationUploaded on: July 3, 2024
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2024 (v1)Publication
Rock permeability is a critical parameter for assessing rock's ability to facilitate fluid flow. The pressure pulse decay method, characterized by its short testing duration and high accuracy, is widely employed for permeability testing of low-permeable rocks. This method acquires pressure differential data by conducting experiments on...
Uploaded on: August 24, 2024 -
2023 (v1)Publication
Background: Copper (Cu) is a trace element that is engaged in various routine physiological processes. Excessive copper exposure can cause damage to organisms; however, it is unknown if the mechanisms underlying the response to Cu2+ among different species are conserved. Methods: Aurelia coerulea polyps and mice models were exposed to Cu2+ to...
Uploaded on: February 11, 2024