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LODRINI , Alessandra Maria

Last name: LODRINI

First name: Alessandra Maria

2022 (v1)

Publication

Metadata-only

Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging

Lazzarini, Edoardo Lodrini, Alessandra Maria Arici, Martina

Rationale: Aging in the heart is a gradual process, involving continuous changes in cardiovascular cells, including cardiomyocytes (CMs), namely cellular senescence. These changes finally lead to adverse organ remodeling and resulting in heart failure. This study exploits CMs from human induced pluripotent stem cells (iCMs) as a tool to model...

Uploaded on: February 14, 2024