LONNQVIST P. A.

Introduction: Ropivacaine is a new long acting amide local anesthetic with properties similar to bupivacaine; studies on adults suggest that ropivacaine is less cardiotoxic, with less dense motor block and similar analgesia . (1,2) At this time no data is available in literature about ropivacaine in pediatrics. Aim of this study is to make a...

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In a double-blind, multicentre study 245 children aged 1-10 yr undergoing elective minor surgery as inpatients were randomly allocated to receive a single caudal extradural injection of 1 ml kg-1 of either 0.25% bupivacaine or 0.2% ropivacaine after induction of light general anaesthesia. The groups were comparable for age, weight, vital signs...

Introduction: Beneficial effects of the a-2 agonist clonidine have recently been reported in children both regarding its use during general anesthesia (Mkawa et al) and following epidural administration (Ivani et al). The pharmacokinetic and hemodynamic profile of clonidine after intravenous administration has also been found acceptable in...