L

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LORÈS , Patrick

Last name: LORÈS

First name: Patrick

2011 (v1)

Journal article

Metadata-only

Escherichia coli Producing CNF1 Toxin Hijacks Tollip to Trigger Rac1-Dependent Cell Invasion

Visvikis, Orane Boyer, Laurent Torrino, Stéphanie

Rho GTPases, which are master regulators of both the actin cytoskeleton and membrane trafficking, are often hijacked by pathogens to enable their invasion of host cells. Here we report that the cytotoxic necrotizing factor-1 (CNF1) toxin of uropathogenic Escherichia coli (UPEC) promotes Rac1-dependent entry of bacteria into host cells. Our...

Uploaded on: December 4, 2022