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LUCHETTI L.

Last name: LUCHETTI L.

2022 (v1)

Publication

Metadata-only

Evolution from a first clinical demyelinating event to multiple sclerosis in the REFLEX trial: Regional susceptibility in the conversion to multiple sclerosis at disease onset and its amenability to subcutaneous interferon beta-1a

Battaglini M. Vrenken H. Tappa Brocci R.

Background and purpose: In the REFLEX trial (ClinicalTrials.gov identifier: NCT00404352), patients with a first clinical demyelinating event (FCDE) displayed significantly delayed onset of multiple sclerosis (MS; McDonald criteria) when treated with subcutaneous interferon beta-1a (sc IFN β-1a) versus placebo. This post hoc analysis evaluated...

Uploaded on: April 14, 2023
2019 (v1)

Publication

Metadata-only

Lifespan normative data on rates of brain volume changes

Battaglini M. Gentile G. Luchetti L.

We provide here normative values of yearly percentage brain volume change (PBVC/y) as obtained with Structural Imaging Evaluation, using Normalization, of Atrophy, a widely used open-source software, developing a PBVC/y calculator for assessing the deviation from the expected PBVC/y in patients with neurological disorders. We assessed...

Uploaded on: March 27, 2023