The cross talk between NK cells and macrophages is emerging as a major line of defense against microbial infections and tumors. This study reveals a complex network of soluble mediators and cell-to-cell interactions allowing human classically activated (M1) macrophages, but not resting (M0) or alternatively activated (M2) macrophages, to prime...
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2015 (v1)PublicationUploaded on: April 14, 2023
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2018 (v1)Publication
Natural Killer cells are the first lymphocyte population to reconstitute early after non myelo-ablative and T cell-replete haploidentical hematopoietic stem cell transplantation with post-transplant infusion of cyclophosphamide. The present study characterizes the transient and predominant expansion starting from the 2nd week after...
Uploaded on: March 27, 2023 -
2021 (v1)Publication
Human V delta 2 cells are innate-like gamma delta T effectors performing potent immune surveillance against tumors. The constitutive expression of NKG2A identifies a subset of V delta 2 T cells licensed with an intrinsic hyper-responsiveness against cancer. Indeed, the transcriptomic profiles of NKG2A(+) and NKG2A(-) cells characterize two...
Uploaded on: April 14, 2023