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LUZZI , Paola

Last name: LUZZI

First name: Paola

2020 (v1)

Publication

Metadata-only

Chronic lymphocytic leukemia cells impair osteoblastogenesis and promote osteoclastogenesis: role of TNFα, IL-6 and IL-11 cytokines

Giannoni, Paolo Marini, Cecilia Cutrona, Giovanna

Bone skeletal alterations are no longer considered a rare event in Chronic Lymphocytic Leukemia (CLL), especially at more advanced stages of the disease. This study is aimed at elucidating the mechanisms underlying this phenomenon. Bone marrow stromal cells, induced to differentiate toward osteoblasts in osteogenic medium, appeared unable to...

Uploaded on: April 14, 2023