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LY TA , Ngoc

Last name: LY TA

First name: Ngoc

2018 (v1)

Journal article

Metadata-only

The tyrosine phosphorylated pro- survival form of Fas intensifies the EGF-induced signal in colorectal cancer cells through the nuclear EGFR/STAT3-mediated pathway OPEN

Ly Ta, Ngoc Chakrabandhu, Krittalak Huault, Sébastien

Tyrosine phosphorylation of Fas (TNFRSF6/CD95) in its death domain turns off Fas-mediated apoptosis, turns on the pro-survival signal, and has implications in different cancers types. We show here that Fas in its pro-survival state, phosphorylated at Y291 (pY291-Fas), functionally interacts with the epidermal growth factor receptor (EGFR), a...

Uploaded on: December 4, 2022