2009 (v1)
Publication
Antiproliferative and preapoptotic activities of a new class of pyrazole derivatives in HL-60 cells.
A series of N-substituted pyrazole derivatives have been synthesized and tested for their anticancer effect on the HL-60 leukaemia cell line. Four were active both in cell-growth inhibition and in inducing apoptosis. The inhibition of cell growth mainly reflects a compound-induced reduction in the number of cells in phases from S to M, whereas...
Uploaded on: April 14, 2023