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2003 (v1)PublicationUploaded on: May 13, 2023
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2005 (v1)Publication
The number of neurotransmitter receptors on the plasma membrane is regulated by the traffic of intracellular vesicles. Golgi-derived vesicles provide newly synthesized receptors to the cell surface, whereas clathrin-coated vesicles are the initial vehicles for sequestration of surface receptors, which are ultimately degraded or recycled. We...
Uploaded on: March 31, 2023 -
2007 (v1)Publication
The amyloid precursor protein (APP) and the presenilins 1 and 2 are genetically linked to the development of familial Alzheimer disease. APP is a single-pass transmembrane protein and precursor of fibrillar and toxic amyloid- peptides, which are considered responsible for Alzheimer disease neurodegeneration. Presenilins are multipass membrane...
Uploaded on: April 14, 2023