Abstract Background: Differentiated thyroid carcinoma offers a good model to investigate the possible correlation between specific gene mutations and chromosome instability. Papillary thyroid neoplasms are characterized by different mutually exclusive genetic alterations, some of which are associated with aneuploidy and aggressive...
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2011 (v1)PublicationUploaded on: March 31, 2023
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2011 (v1)Publication
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Uploaded on: April 14, 2023 -
2016 (v1)Publication
IMPORTANCE Chromosome 6p amplification is associated with more benign behavior for uveal melanomas (UMs) with an otherwise high risk of metastasis conferred by chromosome 3 monosomy. Chromosome 6p contains several members of the B7 family of immune regulator genes, including butyrophilin-like 2 (BTNL2; OMIM, 606000), which is associated with...
Uploaded on: April 14, 2023