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2010 (v1)PublicationUploaded on: April 14, 2023
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2011 (v1)Publication
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2012 (v1)Publication
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2009 (v1)Publication
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2009 (v1)Publication
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2012 (v1)Publication
Despite some advances in understanding of amyotrophic lateral sclerosis (ALS) pathogenesis, significant achievements in treating this disease are still lacking. Mesenchymal stromal (stem) cells (MSCs) have been shown to be effective in several models of neurological diseases. In order to determine the effects of the intravenous injection of...
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2016 (v1)Publication
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2009 (v1)Publication
Nicotinamide phosphoribosyltransferase (Nampt) inhibitors such as FK866 are potent inhibitors of NAD(+) synthesis that show promise for the treatment of different forms of cancer. Based on Nampt upregulation in activated T lymphocytes and on preliminary reports of lymphopenia in FK866 treated patients, we have investigated FK866 for its...
Uploaded on: October 11, 2023