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MAGEZ , Stefan

Last name: MAGEZ

First name: Stefan

June 2009 (v1)

Journal article

Metadata-only

iNOS-producing inflammatory dendritic cells constitute the major infected cell type during the chronic Leishmania major infection phase of C57BL/6 resistant mice.

de Trez, Carl Magez, Stefan Akira, Shizuo

Leishmania major parasites reside and multiply in late endosomal compartments of host phagocytic cells. Immune control of Leishmania growth absolutely requires expression of inducible Nitric Oxide Synthase (iNOS/NOS2) and subsequent production of NO. Here, we show that CD11b+ CD11c+ Ly-6C+ MHC-II+ cells are the main iNOS-producing cells in the...

Uploaded on: December 3, 2022