MAGGI L

Last name: MAGGI L

2014 (v1)

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IL-4-induced gene 1 maintains high Tob1 expression that contributes to TCR unresponsiveness in human T helper 17 cells

Santarlasci V Maggi L Mazzoni A

Human Th17 cells have a limited proliferative capacity compared to other T-cell subsets. We have shown that human Th17 cells display impaired IL-2 production due to IL-4- induced gene 1 (IL4I1) upregulation. Here, we show that in human Th17 cells, IL4I1 also maintains high levels of Tob1, a member of the Tob/BTG (B-cell traslocation...

Uploaded on: March 27, 2023
2012 (v1)

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Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their Expansion

Santarlasci V Maggi L Capone M

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Uploaded on: March 27, 2023
2011 (v1)

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Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

Cosmi L Cimaz R Maggi L

Objective To investigate the phenotype and function of CD4+ T cells in synovial fluid (SF) from the affected joints of children with oligoarticular-onset juvenile idiopathic arthritis (JIA), and to establish a possible link with disease activity. Methods CD4+ T cells were obtained from the peripheral blood (PB) and SF of 23 children with...

Uploaded on: April 14, 2023
2015 (v1)

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Demethylation of the RORC2 and IL17A in human CD4+ T lymphocytes defines Th17 origin of nonclassic Th1 cells

Mazzoni A Santarlasci V Maggi L

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Uploaded on: April 14, 2023

MAGGI L

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