M

MAGNI C. F.

Last name: MAGNI C. F.

2017 (v1)

Publication

Metadata-only

Improvement of ALT decay kinetics by all-oral HCV treatment: Role of NS5A inhibitors and differences with IFN-based regimens

Cento V. Nguyen T. H. T. Di Carlo D.

Background: Intracellular HCV-RNA reduction is a proposed mechanism of action of direct-acting antivirals (DAAs), alternative to hepatocytes elimination by pegylated-interferon plus ribavirin (PR). We modeled ALT and HCV-RNA kinetics in cirrhotic patients treated with currently-used all-DAA combinations to evaluate their mode of action and...

Uploaded on: April 14, 2023