M

M

MAIEL , Majdi

Last name: MAIEL

First name: Majdi

Institution: UCA

Links

September 14, 2018 (v1)

Journal article

Metadata-only

Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells

Grasset, Eloise Bertero, Thomas Bozec, Alexandre

International audience

Uploaded on: December 4, 2022
December 15, 2015 (v1)

Journal article

Metadata-only

Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts

Albrengues, Jean Bertero, Thomas Grasset, Eloise

Carcinoma-associated fibroblasts (CAF) mediate the onset of a proinvasive tumour microenvironment. The proinflammatory cytokine LIF reprograms fibroblasts into a proinvasive phenotype, which promotes extracellular matrix remodelling and collective invasion of cancer cells. Here we unveil that exposure to LIF initiates an epigenetic switch...

Uploaded on: September 5, 2024