M

A

MAIER , A

Last name: MAIER

First name: A

2013 (v1)

Publication

Metadata-only

Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin

CARBONE, Anna PARRINO, Barbara BARRAJA, Paola

2,5-bis(3′-Indolyl)pyrroles, analogues of the marine alkaloid nortopsentin, were conveniently prepared through a three step procedure in good overall yields. Derivatives 1a and 1b exhibited concentration-dependent antitumor activity towards a panel of 42 human tumor cell lines with mean IC50 values of 1.54 μM and 0.67 μM, respectively....

Uploaded on: March 27, 2023