MAIGNE , Lydia

Introduction: In order to optimize hadrontherapy treatments, it is needed to consider the biological effect on irradiated tumor cells. The biological dose can be evaluated through biophysical models, such as the Microdosimetric Kinetic Model (MKM)[1-5]. This model is implemented to take into account a corrected lineal energy spectrum obtained...

Introduction. Pour optimiser les traitements en hadronthérapie, il est primordial de prendre en compte la dose absorbée physique ainsi que l'impact biologique des rayonnements sur les structures irradiées. Pour cela est estimée l'efficacité biologique relative (EBR) qui permet d'évaluer la réponse des cellules à un rayonnement étudié. Ici nous...

International audience

Purpose: Geant4 is a multi-purpose Monte Carlo simulation tool for modeling particle transport in matter. It provides a wide range of settings, which the user may optimize for their specific application. This study investigates GATE/Geant4 parameter settings for proton pencil beam scanning therapy.Methods: GATE8.1/Geant4.10.3.p03 (matching the...

The TIRAMISU collaboration gathers expertise from biologists, physicists, radiochemists and geologists within the Zone-Atelier Territoires Uranifères (ZATU) in France to analyze the radiation exposure of microorganisms living in naturally radioactive mineral springs. These springs are small waterbodies that are extremely stable over geological...

Although many studies have explored the responses of living organisms or ecosystems exposed to radioelements from human activities, very few studies have focused on the characterization of microbial biodiversity and the adaptations developed in environments characterized by natural, chronic and old radioactivity. Radioactive mineral springs are...