Dermatofibrosarcoma protuberans (DFSP) is a rare, dermal neoplasm of intermediate malignancy. It is made of spindle-shaped tumor cells in a storiform pattern positive for CD34. Cytogenetically, DFSP cells are characterized by either supernumerary ring chromosomes composed of sequences derived from chromosomes 17 and 22 or more rarely of...
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June 2008 (v1)Journal articleUploaded on: December 4, 2022
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January 18, 2009 (v1)Journal article
Well-differentiated liposarcomas (WDLPS) and dedifferentiated liposarcomas are cytogenetically characterized by the presence of supernumerary ring or giant chromosomes containing amplified material from the 12q14-15 region. These chromosomes contain neocentromeres, which are able to bind the kinetochore proteins and to ensure a stable mitotic...
Uploaded on: December 3, 2022 -
March 2010 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
March 2010 (v1)Journal article
International audience
Uploaded on: December 3, 2022