M

F

MANETTI , F.

Last name: MANETTI

First name: F.

2009 (v1)

Publication

Metadata-only

Preparation of pyrazolo[3,4-d]pyrimidines and pyrrolo[2,3-d]pyrimidines for treatment of bone related diseases and tumors.

SCHENONE, SILVIA BONDAVALLI, FRANCESCO BRUNO, OLGA

Title compds. [I; X = CH, N; R = H, alkylthio, alkylamino, cycloalkyl, cycloalkylthio, cycloalkylamino, alkyl, etc.; R1 = NHR6, N(R6)2; R6 = alkyl, cycloalkyl, pyrrolidinyl, morpholino, hexahydroazepinyl, (substituted) (hetero)aryl(alkyl)], were prepd. Thus, title compd. (II) (multistep prepn. outlined) after 48 h reduced cellular viability of...

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