MANSUTTI M

Last name: MANSUTTI M

2013 (v1)

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Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of different schedules and treatments

Del Mastro L Fabi A Mansutti M

Background: This open-label study compared docetaxel/gemcitabine vs. paclitaxel/gemcitabine and a weekly (W) vs. 3-weekly (3 W) schedule in metastatic breast cancer (MBC). Methods: Patients relapsed after adjuvant/neoadjuvant anthracycline-containing chemotherapy were randomized to: A) gemcitabine 1000 mg/m(2) Day 1,8 + docetaxel 75 mg/m(2) Day...

Uploaded on: April 14, 2023
2010 (v1)

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A multicentre Phase II study of non-pegylated liposomal doxorubicin in combination with trastuzumab and docetaxel as first-line therapy in metastatic breast cancer

Venturini M Bighin C Puglisi F

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Uploaded on: April 14, 2023
2013 (v1)

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Plasma estrone sulfate concentrations and genetic variation at the CYP19A1 locus in postmenopausal women with early breast cancer treated with letrozole

Lunardi G Piccioli P Bruzzi P

Estrogen synthesis suppression induced by aromatase inhibitors in breast cancer (BC) patients may be affected by single nucleotide polymorphisms (SNPs) of the gene encoding aromatase enzyme, CYP19A1. We assessed the association between plasma estrone sulfate (ES), letrozole treatment, and four SNPs of CYP19A1 gene (rs10046 C > T, rs4646 G > T,...

Uploaded on: March 27, 2023
2014 (v1)

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Body mass index and circulating oestrone sulphate in women treated with adjuvant letrozole

Sini V Lunardi G Cirillo M

Background: Obesity is an independent adverse prognostic factor in early breast cancer patients, but it is still controversial whether obesity may affect adjuvant endocrine therapy efficacy. The aim of our study (ancillary to the two clinical trials Gruppo Italiano Mammella (GIM) 4 and GIM5) was to investigate whether the circulating oestrogen...

Uploaded on: April 14, 2023

MANSUTTI M

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