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MARCINKIEWICZ , Cezary

Last name: MARCINKIEWICZ

First name: Cezary

January 2016 (v1)

Journal article

Metadata-only

Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression

Zakraoui, Ons Marcinkiewicz, Cezary Aloui, Zohra

Lebein, is an heterodimeric disintegrin isolated from Macrovipera lebetina snake venom that was previously characterized as an inhibitor of ADP-induced platelet aggregation. In this study, we investigated the effect of Lebein on the p53-dependent growth of human colon adenocarcinoma cell lines. We found that Lebein significantly inhibited LS174...

Uploaded on: February 28, 2023