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MARCO , Greppi

Last name: MARCO

First name: Greppi

2016 (v1)

Publication

Metadata-only

Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization

PESCE, SILVIA Marco, Greppi Giovanna, Tabellini

Background: PD-1 is an immunologic checkpoint that limits immune responses by delivering potent inhibitory signals to T cells on interaction with specific ligands expressed on tumor/virusinfected cells, thus contributing to immune escape mechanisms. Therapeutic PD-1 blockade has been shown to mediate tumor eradication with impressive clinical...

Uploaded on: April 14, 2023