February 3, 2020 (v1)
Publication
Background: Cancer incidence increases with age. Due to the end-replicative problem, telomeres shorten with each cell division throughout our lives. Telomere shortening has consequences beyond the cellular level. As we age, cells approach replicative senescence and DNA damage emanating by short telomeres initiate a cascade of events that...
Uploaded on: September 5, 2023