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2015 (v1)PublicationUploaded on: April 14, 2023
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2010 (v1)Publication
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2016 (v1)Publication
Immune checkpoints are crucial for the maintenance of self-tolerance and for the modulation of immune responses in order to minimize tissue damage. Tumor cells take advantage of these mechanisms to evade immune recognition. A significant proportion of tumors, including breast cancers, can express co-inhibitory molecules that are important...
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2016 (v1)Publication
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2017 (v1)Publication
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2016 (v1)Publication
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2016 (v1)Publication
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2017 (v1)Publication
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2013 (v1)Publication
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2012 (v1)Publication
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2013 (v1)PublicationCXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2.
Background:Adoptive therapy with tumour-infiltrating lymphocytes (TILs) induces durable complete responses (CR) in ∼20% of patients with metastatic melanoma. The recruitment of T cells through CXCR3/CCR5 chemokine ligands is critical for immune-mediated rejection. We postulated that polymorphisms and/or expression of CXCR3/CCR5 in TILs and the...
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2017 (v1)Publication
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2015 (v1)Publication
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2015 (v1)Publication
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2009 (v1)Publication
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