MARTÍNEZ REINA , Francisco Javier

Que la esperanza de vida aumenta cada día es un hecho evidente, al menos en el mundo desarrollado. En los Estados Unidos, claro exponente de esta porción del mundo, el número de personas mayores de 65 años representaban un 4% de la población total en 1900; a mediados del siglo pasado ese porcentaje era del 8.1 %; actualmente es aproximadamente...

Woven bone is a type of tissue that forms mainly during fracture healing or fetal bone development. Its microstructure can be modeled as a composite with a matrix of mineral (hydroxyapatite) and inclusions of collagen fibrils with a more or less random orientation. In the present study, its elastic properties were estimated as a function of...

Denosumab is one of the most commonly prescribed anti-resorptive drugs for the treatment of postmenopausal osteoporosis. The therapeutic effect of denosumab is to inhibit osteoclast differentiation and consequently bone resorption. Gains in bone mineral density (BMD) are achieved based on the ability of the bone matrix to undergo secondary...

Woven tissue is mainly present in the bone callus, formed very rapidly either after a fracture or in distraction processes. This high formation speed is probably responsible for its disorganized microstructure and this, in turn, for its low stiffness. Nonetheless, the singular volumetric composition of this tissue may also play a key role in...

This study establishes an already defined and tested method to grade exercises of kinematics and dynamics within the course entitled "Theory of Machines and Mechanisms" of the Industrial Technologies Engineering Degree at the Seville School of Engineering (Spain). Particular emphasis is made on the automation of grading and personalization of...

This study establishes an already defined and tested method to grade exercises of kinematics and dynamics within the course entitled "Theory of Machines and Mechanisms" of the Industrial Technologies Engineering Degree at the Seville School of Engineering (Spain). Particular emphasis is made on the automation of grading and personalization of...

Bone remodelling in cortical bone is performed by the so-called basic multicellular units (BMUs), which produce osteons after completing the remodelling sequence. Burger et al. (2003) hypothesized that BMUs follow the direction of the prevalent local stress in the bone. More recently, Martin (2007) has shown that BMUs must be somehow guided by...