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MAURIN , Thomas

Last name: MAURIN

First name: Thomas

March 30, 2007 (v1)

Journal article

Metadata-only

An envelope-determined endocytic route of viral entry allows HIV-1 to escape from secreted phospholipase A2 entry blockade.

Maurin, Thomas Fenard, David Lambeau, Gérard

Secreted phospholipases A(2) (sPLA(2)s) represent a new class of human immunodeficiency virus (HIV) inhibitors that block the early steps of virus entry into cells. Here, we applied an in vitro evolution/selection procedure to select, from primary HIV isolates, an emerging variant (HIV(RBV-3)) able to actively infect cells in the presence of...

Uploaded on: February 28, 2023