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2019 (v1)PublicationUploaded on: April 14, 2023
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2021 (v1)Publication
a B S T r a c T INTRODUCTION: Pericarditis is an inflammatory disease of the pericardium. Progress has been done in recent years in the understanding of its pathophysiology. in particular, preclinical and clinical studies have contributed to increasing our knowledge on the role of interleukin (iL)-1 and NLRP3 (NACHT, leucine-rich repeat, and...
Uploaded on: February 14, 2024 -
2023 (v1)Publication
Acute pericarditis is the most frequent pericardial disease characterized by inflammation of the pericardial layers resulting in pain, dyspnea and fatigue. Often limited to an isolated event, up to 30% of patients experience one or more recurrences. There is limited knowledge about the pathophysiology of this disease, possibly due to the...
Uploaded on: February 13, 2024 -
2019 (v1)Publication
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Uploaded on: April 14, 2023 -
2021 (v1)Publication
After radiation exposure, endothelium-dependent vasorelaxation is impaired due to impaired nitric oxide production. Endothelial dysfunction is characterized by uncoupled endothelial nitric oxide synthase activity, oxidation of the reduced cofactor tetrahydrobiopterin to dihydrobiopterin as one well recognized mechanism. Oral treatment with...
Uploaded on: February 14, 2024 -
2020 (v1)Publication
Pericarditis refers to the inflammation of the pericardial layers, resulting from a variety of stimuli triggering a stereotyped immune response, and characterized by chest pain associated often with peculiar electrocardiographic changes and, at times, accompanied by pericardial effusion. Acute pericarditis is generally self-limited and not...
Uploaded on: April 14, 2023