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MAZZU , A.

Last name: MAZZU

First name: A.

November 30, 2023 (v1)

Journal article

Metadata-only

The mitochondrial NADH shuttle system is a targetable vulnerability for Group 3 medulloblastoma in a hypoxic microenvironment

Contenti, J. Guo, Y. Mazzu, A.

Abstract Medulloblastoma is a cancerous brain tumor that affects mostly children. Among the four groups defined by molecular characteristics, Group 3, the least well characterized, is also the least favorable, with a survival rate of 50%. Current treatments, based on surgery, radiotherapy, and chemotherapy, are not adequate and the lack of...

Uploaded on: January 13, 2025