Las lipocalinas son generalmente proteínas de pequeño tamaño que son secretadas extracelularmente que aunque en un principio han sido clasificadas como proteínas típicamente transportadoras de pequeñas moléculas hidrófobas, la visión actual es que las lipocalinas cubren un abanico de funciones diverso y todavía no totalmente comprendido....
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March 30, 2016 (v1)PublicationUploaded on: December 5, 2022
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April 15, 2019 (v1)Publication
The Lipocalin family is a group of homologous proteins characterized by its big array of functional capabilities. As extracellular proteins, they can bind small hydrophobic ligands through a well-conserved β-barrel folding. Lipocalins evolutionary history sprawls across many different taxa and shows great divergence even within chordates. This...
Uploaded on: December 4, 2022 -
June 23, 2020 (v1)Publication
The Lipocalin Apolipoprotein D (ApoD) is one of the few genes consistently overexpressed in the aging brain, and in most neurodegenerative and psychiatric diseases. Its functions include metabolism regulation, myelin management, neuroprotection, and longevity regulation. Knowledge of endogenous regulatory mechanisms controlling brain...
Uploaded on: March 27, 2023