MEUCCI G.

A phase I/II clinical trial on autologous hematopoietic stem cell transplantation (AHSCT) was conducted hy 15 Italian neurological and hematological centers after reaching a consensus on patient selection criteria, primary endpoint and treatment regimen. The study was designed to investigate magnetic resonance imaging (MRI) and laboratory...

Background: Autologous hematopoietic stem cell transplantation (ASCT) has been recently utilized with encouraging results in patients with poorly controlled MS. Objective: To determine in severe cases of MS the effect of ASCT on gadolinium (Gd)-enhanced MRI and to obtain information on clinical course and safety. Methods: In a cooperative...