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MIGLIORINO , Maria Rita

Last name: MIGLIORINO

First name: Maria Rita

2022 (v1)

Publication

Metadata-only

High familial burden of cancer correlates with improved outcome from immunotherapy in patients with NSCLC independent of somatic DNA damage response gene status

Cortellini, Alessio Giusti, Raffaele Filetti, Marco

Family history of cancer (FHC) is a hallmark of cancer risk and an independent predictor of outcome, albeit with uncertain biologic foundations. We previously showed that FHC-high patients experienced prolonged overall (OS) and progression-free survival (PFS) following PD-1/PD-L1 checkpoint inhibitors. To validate our findings in patients with...

Uploaded on: April 14, 2023