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2019 (v1)PublicationUploaded on: March 27, 2023
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2019 (v1)Publication
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Uploaded on: March 27, 2023 -
2021 (v1)Publication
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Uploaded on: April 14, 2023 -
2020 (v1)Publication
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Uploaded on: April 14, 2023 -
2020 (v1)Publication
Background: Hyperferritinemic syndromes are systemic inflammatory disorders characterized by a dysfunctional immune response, which leads to excessive activation of the monocyte-macrophage system with hypercytokinemia and may pursue a rapidly fatal course. Case presentation: We describe two patients of 11 and 9 years of age with...
Uploaded on: April 14, 2023 -
2019 (v1)Publication
Objective. To seek predictors of therapeutic response to the interleukin (IL)-1 inhibitor anakinra in children with systemic-onset juvenile idiopathic arthritis (sJIA). Methods. The clinical charts of all patients with sJIA who were newly treated with anakinra at our center between 2004 and 2017 were reviewed retrospectively. Predictors...
Uploaded on: April 14, 2023 -
2023 (v1)Publication
Juvenile systemic lupus erythematosus (jSLE) is a complex inflammatory autoimmune disorder. In the last decades, genetic factors and activation pathways have been increasingly studied to understand their potential pathogenetic role better. Genetic and transcriptional abnormalities directly involved in the type I interferon (IFN) signaling...
Uploaded on: July 3, 2024 -
2021 (v1)Publication
Objective: To describe the clinical characteristics, treatment, and outcomes of a multinational cohort of patients with macrophage activation syndrome (MAS) and thrombotic microangiopathy (TMA). Study design: International pediatric rheumatologists were asked to collect retrospectively the data of patients with the co-occurrence of MAS and TMA....
Uploaded on: April 14, 2023